1. Astrobiology & Extreme Environments
We study cyanobacteria to define the limits of life in extreme terrestrial and extraterrestrial environments. Using specialized atmosphere and stellar simulators, we recreate conditions found on Mars (low pressure, high CO2) and planets orbiting alternative stars (M-dwarfs for example). By analyzing molecular adaptations, such as specialized DNA repair and protective pigments, we model the habitability of other worlds and guide the search for life in the cosmos
2. Nitrogen Fixation in Anabaena
To solve the “oxygen paradox”, performing O2-sensitive nitrogen fixation alongside oxygenic photosynthesis, the cyanobacterium Anabaena differentiates specialized cells called heterocysts. These cells provide an anaerobic home for the nitrogenase enzyme while receiving energy from neighboring vegetative cells. We study molecular mechanisms to achieve this process, utilizing genetically encoded sensors to measure metabolic fluxes in real-time
3. Sustainable Bioplastics (PHB)
We utilize cyanobacteria as sustainable “cell factories” to produce Polyhydroxybutyrate (PHB), a biodegradable alternative to petroleum-based plastics. By photosynthetic activity, these microalgae convert CO2 directly into PHB granules. Our research optimizes genetic engineering and culture parameters to maximize yield and molecular weight, paving the way for carbon-neutral, large-scale bioplastic production